Research Priorities
The Genomics & Bioinformatics Core Facility (GBCF) at the University of Notre Dame provides essential services to a diverse research community engaged in various areas of study, including basic biomedical research, vector disease research, population genomics, and environmental genomics. We leverage cutting-edge technologies such as Illumina sequencing, single-cell analysis, and spatial transcriptome analysis to facilitate comprehensive data acquisition for a wide range of applications.
Our services cover several important genomic and bioinformatic disciplines, including:
-
Cancer Genomics: Studying the genetic alterations underlying cancer development and progression, aiding in personalized medicine approaches.
-
Transcriptomics: Profiling gene expression patterns to gain insights into cellular functions, developmental processes, and disease mechanisms.
-
Epigenomics: Studying modifications to DNA and associated proteins that regulate gene expression and influence cellular phenotype.
-
Microbial Genomics: Analyzing the genomes of microorganisms to comprehend their diversity, evolution, and potential impact on health and ecosystems.
-
Metagenomics: Investigating genetic material recovered directly from environmental samples to understand microbial communities and their functions.
Our facility offers tailored guidance and analysis workflows to meet the specific needs of researchers working with both model and non-model systems. We employ robust bioinformatics tools and biocomputing resources to handle complex datasets generated from high-throughput sequencing technologies.
Key features of our services include:
-
Customized Analysis: Developing customized bioinformatics pipelines tailored to unique research questions and experimental designs.
-
Data Interpretation: Providing comprehensive data interpretation and visualization to extract meaningful insights from complex genomic datasets.
-
Consultation and Training: Offering consultation and training on experimental design, data analysis strategies, and interpretation of results to empower researchers in genomics and bioinformatics.
The GBCF at the University of Notre Dame is committed to supporting innovative research by delivering high-quality genomic and bioinformatic solutions, enabling researchers to advance understanding, and make impactful discoveries across diverse scientific disciplines.